Microsoft’s Comfort Optical 3000 Mouse allows the user to zoom in on the cursor with the click of a mouse button. Although, I have not tried it yet, it seems like a great little feature for visually-impaired users.
I am quite happy with my wireless Logitech mouse. It is quite configurable, so I could probably assign one of its many buttons to Vista’s magnification program, thus replicating the Comfort Optical 3000′s magnification feature. I do not find myself using the built in magnifaction software much, so I have not tried this out. Also, if you are a big user of screen magnification software, like zoomtext, this mouse may be more complicating thatn helpful.
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